Publication

update: 06-10-2024

Fu, M.#; Han, X.#; Chen B.; Guo, L.; Zhong, L.; Hu, P.; Pan, Y.; Qiu, M.*; Cao, P.*; Chen, J*, Cancer treatment: from traditional Chinese herbal medicine to the liposome delivery system. Acta Materia Medica 2022, 1(4), 486-506.
Chen, J.#; Ye, Z.#; Huang, C.; Qiu, M.; Song, D.; Xu, Q.*, Lipid nanoparticle-mediated lymph node-targeting delivery of mRNA cancer vaccine elicits robust CD8+ T cell response. Proc. Natl. Acad. Sci. U. S. A. 2022, 119, e2207841119.
Xiao, Q.#; Zoulikha, M.#; Qiu, M.#; Teng, C.; Lin, C; Li, X; Sallam, M.; Xu, Q.*; He, W.*, The effects of protein corona on invivo fate of nanocarriers. Adv. Drug Deliv. Rev. 2022, 186, 114356. (Invited review)
Qiu, M.#; Tang, Y.#,*; Chen, J. #; Muriph, R.; Ye, Z.; Huang, C.; Evans, J.; Henske, E.*; Xu, Q.*, Lung-selected mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis. Proc. Natl. Acad. Sci. U. S. A. 2022, 119, e2116271119. ESI Highly Cited Paper.
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Qiu, M.#; Li, Y. #; Bloomer, H.; Xu, Q.*, Developing biodegradable lipid nanoparticles for intracellular mRNA delivery and genome editing. Acc. Chem. Res. 2021, 54, 4001-4011. (Special issue: mRNA therapeutics. Invited review)
Chen, J.#; Qiu, M.#; Ye, Z.; Thomas, N.; Li, Y.; Glass, Z.; Zhao, X.; Yang, L.; Chen, J.; Xu, Q.*, In situ cancer vaccination using lipidoid nanoparticles. Sci. Adv. 2021, 7, eabf1244.
Qiu, M.#; Glass, Z.#; Chen, J.; Haas, M.; Jin, X.; Zhao, X.; Rui, X.; Ye, Z.; Li, Y.; Zhang, F; Xu, Q.*, Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single guide RNA achieves liver-specific in vivo genome editing of Angptl3. Proc. Natl. Acad. Sci. U. S. A. 2021, 118, e2020401118. ESI Highly Cited Paper.
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Chen, J.; Qiu, M.; Ma, F.; Yang, L.; Glass, Z., Xu, Q.*, Enhanced protein degradation by intracellular delivery of pre-fused PROTACs using lipid-like nanoparticles. J. Control. Release 2021, 330, 1244-1249.
Zhao, X.#; Chen, J.#; Qiu, M.; Li, Y.; Glass, Z.; Xu, Q.*, Imidazole‐based synthetic lipidoids for in vivo mRNA delivery into primary T lymphocytes. Angew. Chem. Int. Ed. 2020, 132, 2-9.
Li, S.#; Qiu, M.#; Guo, j.; Zhao, X.; Zhong, Z.*; Deng, C.*, Coating-sheddable CD44-targeted poly(D,L-lactide-co-glycolide) nanomedicines fabricated by using photoclick-crosslinkable surfactant. Adv. Therapeutics 2020, 3, 1900160. (Invited article)
Wang, X.; Qiu, M.; Deng, C.; Cheng, R.*; Zhong, Z.*, Targeted and reduction-sensitive crosslinked PLGA nanotherapeutics for safer and enhanced chemotherapy of malignant melanoma. ACS Biomater. Sci. Eng. 2020, 6, 2621-2629. (Invited article. Special Issue: Leaders in Biomedical Engineering)
Qiu, M.#; Glass, Z.#; Xu, Q.*, Non-viral nanoparticles for CRISPR-based genome editing: is it just a simple adaption of what have been developed for nucleic acid delivery?. Biomacromolecules 2019, 20, 3333-3339. (Invited review. Virtual Issue: Biomacromolecules for Emerging Biological and Medical Science and Technology to celebrate Biomacromolecules 20th Anniversary)
Qiu, M.; Ouyang, J.; Wei, Y.; Zhang, J.; Lan, Q.; Deng, C.*; Zhong, Z.*, Selective cell penetration peptide-functionalized envelope-type chimeric lipopepsomes boost systemic RNAi therapy for lung tumors. Adv. Healthc. Mater. 2019, 8, 1900500.
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Qiu, M.; Zhang, Z.; Wei, Y.; Sun, H.; Zhang, J.; Meng, F.; Deng, C.*; Zhong, Z.*, Small-sized and robust chimaeric lipopepsomes: A simple and functional platform with high protein loading for targeted intracellular delivery of protein toxin in vivo. Chem. Mater. 2018, 30, 6831-6838.
Rades, N.; K Achazi, K.; Qiu, M.; Deng, C.; Haag, R.; Zhong, Z.*; Licha, K.*, Reductively cleavable polymer-drug conjugates based on dendritic polyglycerol sulfate and monomethyl auristatin E as anticancer drugs. J. Control. Release 2018, 300, 13-21.
Qiu, M.; Wang, X.; Sun, H.; Zhang, J.; Deng, C.*; Zhong, Z.*, Cyclic RGD peptide micelles for enhanced loading and targeted delivery of monomethyl auristatin E. Mol. Pharmaceutics 2018, 15, 4854-4861.
Qiu, M.; Sun, H.; Meng, F.; Cheng, R.; Zhang, J.; Cheng, L.; Deng, C.*; Zhong, Z.*, Lipopepsomes as a robust nanoplatform for highly efficient encapsulation and tumor-targeted delivery of doxorubicin hydrochloride. J. Control. Release 2018, 272, 107-113.
Qiu, M.; Ouyang, J.; Sun, H.; Meng, F.; Cheng, R.; Zhang, J.; Cheng, L.; Lan, Q.; Deng, C.*; Zhong, Z.*, Biodegradable micelles based on poly(ethylene glycol)-b-polylipopeptide copolymer: a robust and versatile nanoplatform for anticancer drug delivery. ACS Appl. Mater. Interfaces 2017, 9, 27587-27595.
Gu, X.; Qiu, M.; Sun, H.; Zhang, J.; Cheng, L.; Deng, C.; Zhong, Z., Polytyrosine nanoparticles enable ultra-high loading of doxorubicin and rapidly enzyme-responsive drug release. Biomater. Sci. 2018, 6, 1526-1534.
Chen, T.; Qiu, M.; Zhang, J.; Sun, H.; Deng, C.; Zhong, Z., Integrated multifunctional micelles co-self-assembled from polypeptides conjugated with natural ferulic acid and lipoic acid for efficient and bioresponsive doxorubicin delivery. ChemPhysChem 2018, 19, 2070-2077. (Invited article)
Zhong, P.; Qiu, M.; Zhang, J.; Sun, H.; Cheng, R.; Deng, C.; Meng, F.; Zhong, Z., cRGD-installed docetaxel-loaded mertansine prodrug micelles: redox-triggered ratiometric dual drug release and targeted synergistic treatment of B16F10 melanoma. Nanotechnology 2017, 28, 295103.
Chen, P.; Qiu, M.; Deng, C.; Meng, F.; Zhang, J.; Cheng, R.; Zhong, Z., pH-responsive chimaeric pepsomes based on asymmetric poly (ethylene glycol)-b-poly (L-leucine)-b-poly (L-glutamic acid) triblock copolymer for efficient loading and active intracellular delivery of doxorubicin hydrochloride. Biomacromolecules 2015, 16, 1322-1330.